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Indicatively, with an additional dopamine-regulating effect, BPC 157 counteracted the models of the positive-like and negative-like similar symptoms in schizophrenia rat models [171,200]

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The pivotal trial supporting its 2010 FDA approval enrolled 816 HIV-infected adults with clinically defined lipodystrophy, and Phase 3 data documented visceral fat reductions of roughly 15-18% over 26 weeks of treatment a result robust enough to clear FDA review for a defined medical indication